PHARMACOMETRICS PUBLICATIONS
I am a strong advocate for sharing pharmacometrics knowledge. Below, I provide links to some of my pharmacometrics publications in chronological order. Please note that access to some publications may require a subscription
2021
2020
Mario González-Sales, Olivier Barriere, Pierre-Olivier Tremblay, Guillaume Bonnefois, Julie Desrochers, and Fahima Nekka.
Assembling Pharmacometric Datasets in R – The puzzle Package.
2019
Sumit Basu, Haitao Yang, Lanyan Fang, Mario González-Sales, Liang Zhao, Mirjam M Trame, Lawrence Lesko, and Stephan Schmidt.
Physiologically Based Pharmacokinetic Modeling to Evaluate Formulation Factors Influencing Bioequivalence of Metoprolol Extended‐Release Products.
2017
Mario González-Sales, Lanyan Fang, and Liang Zhao.
Model-Based Assessment Using Conventional Bioequivalence Limits to Ensure Safety and Efficacy of Rivaroxaban in Patients Undergoing Hip or Knee Replacement.
2017
Mario González-Sales, Fahima Nekka, Mario Tanguay, Pierre-Olivier Tremblay, and Jun Li.
Modelling the dose-response relationship: the fair share of pharmacokinetic and pharmacodynamic information.
2016
Morgan Craig, Mario González-Sales, Jun Li, and Fahima Nekka.
Approaching Pharmacometrics as a Paleontologist Would: Recovering the Links Between Drugs and the Body Through Reconstruction.
2016
Mario González-Sales, Olivier Barriere, Pierre-Olivier Tremblay, Fahima Nekka, Julie Desrochers, and Mario Tanguay.
Modeling Testosterone Circadian Rhythm in Hypogonadal Males: Effect of Age and Circannual Variations.
2015
Mario González-Sales, Olivier Barriere, Pierre-Olivier Tremblay, Fahima Nekka, Jean-Claude Mamputu, Silvie Boudreault, and Mario Tanguay.
Population Pharmacokinetic and Pharmacodynamic Analysis of Tesamorelin in HIV-infected Patients and Healthy Subjects.
2015
Mario González-Sales, Olivier Barriere, Pierre-Olivier Tremblay, Fahima Nekka, Jean-Claude Mamputu, Silvie Boudreault, and Mario Tanguay.
Population Pharmacokinetic Analysis of Tesamorelin in HIV-infected Patients and Healthy Subjects.
2013
Belén Valenzuela, Mario González-Sales, Vanesa Escudero Ortiz, E. Martínez Navarro, Carlos Pérez Ruixo, J. Rebollo Liceaga, R. González Manzano, Juan Jose Pérez Ruixo.
Influence of genetic polymorphisms in UGT1A1, UGT1A7 and UGT1A9 on the pharmacokynetics of irinotecan, SN-38 and SN-38G.
2012
Mario González-Sales, Belén Valenzuela, Carlos Pérez Ruixo, Carlos Fernández Teruel, Bernardo Miguel-Lillo, Arturo Soto-Matos, Juan Jose Pérez Ruixo.
Population Pharmacokinetic-Pharmacodynamic Analysis of Neutropenia in Cancer Patients Treated with PM00104 (Zalypsis).
2012
Carlos Pérez Ruixo, Belén Valenzuela, Carlos Fernández Teruel, Mario González-Sales, Bernardo Miguel-Lillo, Arturo Soto-Matos, Juan Jose Pérez Ruixo.
Population Pharmacokinetics of PM00104 (Zalypsis) in Cancer Patients.